Dr. Manash Pratim Pathak

Dr. Manash Pratim Pathak

Dr. Manash Pratim Pathak

About

Specialization:
Pharmacology

Qualification

Qualification Board/University Year
PhD Dibrugarh University & DRDO 2021
M.Pharm Sikkim University 2013
B.Pharm University of North Bengal 2010

 

Personal Interest

Listening to music, reading books.

Working Experience

Year Organization Position Responsibilities
September, 2013 to June, 2014

Assam Agriculture University. Guwahati Campus, Assam. India.

Junior Research Fellow Pharmacological Research
March, 2015 to February, 2020
  1. Dibrugarh University, Dibrugarh, Assam, India.
  2. Defence Research Laboratory, Tezpur, Assam, India
Doctoral Research Scholar

Pharmacological Research

February, 2020 to April, 2021 Pratiksha Institute of Pharmaceutical Sciences, Guwahati. Assam, India Assistant Professor Teaching and Research
June, 2021 to July, 2023 Assam down town University, Guwahati. Assam, India Assistant Professor Teaching and Research
August, 2023 to Present Assam down town University, Guwahati. Assam, India Associate Professor Teaching and Research

 

Research

Project Name

Role

Amount Approved/Sanctioned

Host Institute

Funding agency

Sanction Date

Status

Development and evaluation of a polyherbal infusion against obesity
and related co-morbidities in high-fat diet-fed rodent model

Principal Investigator & Coordinator

INR 5,00,000.00

Assam down town University, Guwahati. Assam, India

Assam down town University, Guwahati. Assam, India

18/02/22

Completed

Pharmacological Exploration of Anti-PCOS Properties of Selected Medicinal Plants from Northeast India in Experimentally Obese Animals and Developing an AI-Based Prediction Tool for PCOS in Young Women

Principal Investigator & Coordinator

INR 5,00,000.00

Assam down town University, Guwahati. Assam, India

Assam down town University, Guwahati. Assam, India

09/10/23

Ongoing

Systematic pharmacological investigation of bioactive phytoconstituents present in medicinal plants found in the northeastern region of India against obesity-associated non-alcoholic fatty liver disease

Principal Investigator

INR 51,28,252.00

Assam down town University, Guwahati. Assam, India

Indian Council of Medical Research, Govt. of India

01/02/2023

Ongoing

2024:

1. Barbhuiya, P.A., Ahmed, A., Dutta, P.P., Sen, S., Pathak, M.P., Mitigating Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): The Role of Bioactive Phytoconstituents in Indian Culinary Spices. Current Nutrition Reports. (Accepted) (IF: 4.6)

2. Barbhuiya, P.A., Pathak, M.P., Impact of Obesity, Menopause and Depression in Women’s Health: Deciphering the Complex Relationship. Current Medicinal Chemistry. 2024. 32 ():e09298673317600 (IF: 3.5)

3. Ahmed, L.A., Hussain, A., Barbhuiya, P.A., Zaman, S.,  Laskar, A.M., Pathak, M.P., Dutta, P.P., Sen, S. Herbal Medicine for Management of Wound: A Review of Clinical Trials. Infectious Disorders-Drug Targets. 2024. (Accepted)

4. Barbhuiya, P.A., Pariong, D., Alam, A.P., Mazumder, T.M.S.R., Sarma, S., Sen, S. and Pathak, M.P., Ameliorative Effects of Essential Oils on Diabetes Mellitus: A Review. Current topics in medicinal chemistry. 2024. 24():e15680266314922. (IF: 2.9)

5. Barbhuiya, P.A. and Pathak, M.P., 2024. Myrtenol: A Promising Terpene with Potent Pharmacological Properties. Pharmacological Research-Natural Products, p.100067.

6. Patowary, P., Pathak, M.P., Goyary, D., Kishor, S., Zaman, K., Chattopadhyay, P., Toll Like Receptors: a Promising Target for COVID 19 Mediated Acute Respiratory Distress Syndrome. Annals of Multidisciplinary Research, Innovation and Technology. 2024. 3(1): 23-30.

7. Nath D, Barbhuiya PA, Sen S, Pathak MP. Review On In-Vivo And In-Vitro Models Of Obesity And Obesity-Associated Co-Morbidities. Endocrine, Metabolic and Immune Disorders-Drug Targets; 2024; 20, pp. (IF: 1.9)

8. Patowary P, Pathak MP, Barbhuiya PA, Karmakar S, Chattopadhyay P, Zaman, K. Oleoresin Capsicum (OC) Spray: An Assessment of Respiratory Health and its Management Following Accidental and Deliberate Exposures. Current Topics in Medicinal Chemistry. 2024. (IF: 3.4)

9. Karmakar M, Chakraborty B, Hussain AS, Barbhuiya PA, Chang NY, Warjri I, Pathak MP. A Systemic Review of Pre-clinical Studies of Herbal Plants having Anti-Polycystic Ovarian Syndrome Activity: A PAN-India Study. The Natural Products Journal. 2024;14. (IF: 0.7)

10. Mawia D, Das A, Umbon Y, Saikia R, Pathak K, Pathak MP. An Insight into the Mechanism, Safety and Efficacy for Photoprotectionand Dermatological Conditions of Polypodium leucotomos Extract. The Natural Products Journal. 2024;14(7):e190124225828. (IF:0.7)

11. Pathak K, Pathak MP, Saikia R, Gogoi U, Sahariah JJ, Das A, et al. Cardioprotective Activities of some Indian Spices: An Insight into Pharmacology and Phytochemical Investigation. Current Traditional Medicine. 2024;10(1):e100223213570. (IF: 0.6)

12. Saikia R, Pathak K, Das A, Tayeng D, Ahmad MZ, Das J, Pathak MP, et al. Design, QSAR Methodology, Synthesis and Assessment of Some Structurally Different Xanthone Derivatives as Selective Cox-2 Inhibitors for their Anti-inflammatory Properties. Medicinal Chemistry. 2024;20(1):78–91. (IF: 2.3)

13. Barbhuiya PA, Dey J, Saikia K, Ishtiyak ST, Aqib AB, Marshillong KL, Gogoi J, Wankhar W,  Sarma S,  Sen S, Pathak MP. Herbal tea used globally targeting metabolic syndrome: A systematic review. International Journal of Diabetes in Developing Countries. 2024;11. (IF: 0.7)

14. Pathak K, Ahmad MZ, Saikia R, Pathak MP, Sahariah JJ, Kalita P, et al. Nanomedicine: A New Frontier in Alzheimer’s Disease Drug Targeting. Central Nervous Systsem Agents in Medicinal Chemistry. 2024,28.

15. Pathak MP, Patowary P, Chattopadhyay P, Barbhuiyan PA, Islam J, Gogoi J, et al. Obesity-associated Airway Hyperresponsiveness: Mechanisms Underlying Inflammatory Markers and Possible Pharmacological Interventions. Endocrine, Metabolic and Immune Disorders-Drug Targets. 2024;24(9):1053–68. (IF: 2)

16. Kalita N, Pathak MP, Roy S, Barbhuiya PA, Saikia L, Mazumder TMSR, et al. Prospects of Repurposed Drugs in Diabetes Mellitus: A Current Update. Current Drug Therapy. 2024;19. (IF: 0.3)

17. Pathak K, Pathak MP, Saikia R, Gogoi U, Das RJ, Patowary P, et al. Therapeutic Repurposing of Antidiabetic Drugs in Diabetes-associated Comorbidities. Current Drug Therapy. 2024,19(2):178–94. (IF: 0.3)

2023:

18. Pathak M, Patowary P, Das A, Sen S, Dey B, Chattopadhay P, et al. A Pragmatic Plan for a COVID-19 Combat-ready Improvised Face mask with an Anti-viral filter: Utilizing North-East Indian Medicinal Plants. Annals of Multidisciplinary Research, Innovation and Technology. 2023;2:54–60.

19. Barbhuiya PA, Sen S, Pathak MP. Ameliorative role of bioactive phytoconstituents targeting obesity associated NAFLD by modulation of inflammation and lipogenesis pathways: a comprehensive review. Phytochemistry Reviews. 2023. (IF: 7.3)

20. Barbhuiya PA, Arman S, Paul H, Sen S, Dey BK, Pathak MP. An Updated Review on the Early Detection and Drug Development Targeting Breast Cancer. Current Womens Health Reviews. 2024,20(4):e130723218685. (IF: 0.3)

21. Das A, Pathak MP, Pathak K, Saikia R, Gogoi U. Herbal medicine for the treatment of obesity-associated asthma: a comprehensive review. Frontiers in Pharmacology. 2023,14:1186060. (IF: 4.4)

22. Ahmad MZ, Ahmad J, Umar A, Abdel-Wahab BA, Lahiq AA, Khan ZN, Pathak K, Rizwanullah M, Warsi MH, Saikia R, Pathak MP. Nanomaterials in Cancer Immunotherapy: A Spotlight on Breast Cancer. Science of Advanced Materials. 2023;15(3):285–318. (IF: 1.474)

23. Pathak K, Saikia R, Sarma H, Pathak MP, Das RJ, Gogoi U, et al. Nanotheranostics: application of nanosensors in diabetes management. Journal of Diabetes and Metabolic Disorders. 2023;22(1):119–33. (IF: 1.8)

24. Chanu NR, Gogoi P, Barbhuiya PA, Dutta PP, Pathak MP, Sen S. Natural Flavonoids as Potential Therapeutics in the Management of Diabetic Wound: A Review. Current Topics in Medicinal Chemistry. 2023;23(8):690–710. (IF: 3.4)

25. Gogoi U, Pathak K, Saikia R, Pathak MP, Paul T, Khan SA, et al. Recent Advances on Natural and Non-Natural Xanthones as Potential Anticancer Agents: A Review. Medicinal Chemistry. 2023;19(8):757–84. (IF: 2.3)

26. Pathak MP, Pathak K, Saikia R, Gogoi U, Patowary P, Chattopadhyay P, et al. Therapeutic potential of bioactive phytoconstituents found in fruits in the treatment of non-alcoholic fatty liver disease: A comprehensive review. Heliyon. 2023;9(4):e15347. (IF: 3.4)

27. Bhattacharjee R, Pathak K, Das J, Bordoloi S, Pathak MP, Barbhuiya PA, et al. Therapeutic Potential of Gut Microbiota in Child Health. Anti-infective Agents. 2023;21(4):e180523217048.

28. Kumar M, Zaman MdK, Das S, Goyary D, Pathak MP, Chattopadhyay P. Transient Receptor Potential Vanilloid (TRPV4) channel inhibition: A novel promising approach for the treatment of lung diseases. Biomedicine & Pharmacotherapy. 2023;163:114861. (IF: 6.9)

2022:

29. Pathak K, Pathak MP, Saikia R, Gogoi U, Sahariah JJ, Zothantluanga JH, et al. Cancer Chemotherapy via Natural Bioactive Compounds. Current Drug Discovery Technologies. 2022;19(4):e310322202888.

30. Barbhuiya PA, Laskar AM, Mazumdar H, Dutta PP, Pathak MP, Dey BK, et al. Ethnomedicinal Practices and Traditional Medicinal Plants of Barak Valley, Assam: a systematic review. Journal of Pharmacopuncture. 2022;25(3):149–85.

31. Pathak MP, Pathak K, Saikia R, Gogoi U, Ahmad MZ, Patowary P, et al. Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review. Biomedicine & Pharmacotherapy. 2022;149:112901. (IF: 6.9)

32. Das P, Ahmed S, Dutta P, Gogoi P, Pathak M, Dey B, et al. Plants with Analgesic and Anti-Inflammatory Potential: A Review on Folk Medicinal Plants of Upper Assam, India. Annals of Multidisciplinary Research, Innovation and Technology. 2022;1:35–47.

2021:

33. Chakrabarti S, Mazumder B, Rajkonwar J, Pathak MP, Patowary P, Chattopadhyay P. bFGF and collagen matrix hydrogel attenuates burn wound inflammation through activation of ERK and TRK pathway. Scientific Reports. 2021;11(1):3357. (IF: 3.8)

34. Pathak MP, Patowary P, Das A, Goyary D, Karmakar S, Bhutia YD, et al. Crosstalk between AdipoR1/AdipoR2 and Nrf2/HO‐1 signal pathways activated by β‐caryophyllene suppressed the compound 48/80 induced pseudo‐allergic reactions. Clinical and Experimental Pharmacology and Physiology. 2021;48(11):1523–36. (IF: 2.4)

35. Gogoi U, Das A, Pathak MP, Chattopadhyay P, Johari S. Design, Synthesis, Computational and Biological Evaluation of Two New Series of 1, 3- and 1,6-dihydroxy Xanthone Derivatives as Selective COX-2 Inhibitors. Letters in Drug Design & Discovery. 2021;18(9):884–914. (IF: 1)

36. Sen S, Chakraborty R, Kalita P, Pathak MP. Diabetes mellitus and COVID-19: Understanding the association in light of current evidence. World Journal of Clinical Cases. 2021;9(28):8327–39. (IF: 1)

37. Pathak MP, Patowary P, Goyary D, Das A, Chattopadhyay P. β-caryophyllene ameliorated obesity-associated airway hyperresponsiveness through some non-conventional targets. Phytomedicine. 2021;89:153610. (IF: 6.7)

2020:

38. Patowary P, Pathak MP, Kishor S, Roy PK, Das S, Chattopadhyay P, et al. Cardiopulmonary function and dysregulated cardiopulmonary reflexes following acute oleoresin capsicum exposure in rats. Toxicology and Applied Pharmacology. 2020;405:115188. (IF: 3.3)

39. Pathak MP, Das A, Patowary P, Chattopadhyay P. Contentious role of ‘Good Adiponectin’ in pulmonary and cardiovascular diseases: Is adiponectin directed therapy a boon or a bane? Biochimie. 2020;175:106–19. (IF: 3.3)

40. Patowary P, Pathak MP, Zaman K, Dwivedi SK, Chattopadhyay P. Innate inflammatory response to acute inhalation exposure of riot control agent oleoresin capsicum in female rats: An interplay between neutrophil mobilization and inflammatory markers. Experimental Lung Research. 2020;46(3-4):81-97. (IF:1.7)

41. Chattopadhyay P, Pathak MP, Patowary P, Chakrabarti S, Goyary D, Karmakar S, et al. Synthesized atropine nanoparticles ameliorate airway hyperreactivity and remodeling in a murine model of chronic asthma. Journal of Drug Delivery Science and Technology. 2020;56:101507. (IF: 4.5)

2019:

42. Mandal S, Pathak MP, Sharma Bora N, Patowary P, Barman PK, Kishor S, et al. Determination of LCt 50 of aerosolized paraquat and its pulmonary toxic implications in non-anesthetized rats. Drug and Chemical Toxicology. 2019;42(5):552–8. (IF: 2.6)

43. Marbaniang D, Das RJ, Pal P, Saikia A, Pathak MP, Mandal S, Bora NS, Das AK, Chattopadhyay P, Ray S, Mazumder B. Extended Release Floating Microballoons Containing Clerodendrum colebrookianum Extract: In vitro in vivo Evaluation. Indian Journal of Pharmaceutical Education and Research. 2019;53(3). pp. S246-S254.

2018:

44. Pathak MP, Policegoudra RS, Goyary D, Das A, Mandal S, Chakraborti S, et al. Safety evaluation of an oat grain alkaloid gramine by genotoxicity assays. Drug and Chemical Toxicology. 2018;41(2):147–54. (IF: 2.6)

2017:

45. Islam J, Zaman K, Chakrabarti S, Bora NS, Pathak MP, Mandal S, et al. Exploration of ethyl anthranilate-loaded monolithic matrix-type prophylactic polymeric patch. Journal of Food and Drug Analysis. 2017;25(4):968–75. (IF: 3.6)

46. Patowary P, Pathak MP, Zaman K, Raju PS, Chattopadhyay P. Research progress of capsaicin responses to various pharmacological challenges. Biomedicine & Pharmacotherapy. 2017;96:1501–12. (IF: 6.9)

47. Bora NS, Pathak MP, Mandal S, Mazumder B, Policegoudra R, Raju PS, et al. Safety assessment and toxicological profiling of a novel combinational sunprotective dermal formulation containing melatonin and pumpkin seed oil. Regulatory Toxicology and Pharmacology. 2017;89:1–12. (IF: 3.0)

48. Basu A, Das AS, Sharma M, Pathak MP, Chattopadhyay P, Biswas K, et al. STAT3 and NF-κB are common targets for kaempferol-mediated attenuation of COX-2 expression in IL-6-induced macrophages and carrageenan-induced mouse paw edema. Biochemistry and Biophysics Reports. 2017;12:54–61. (IF: 2.3)

49. Islam J, Zaman K, Chakrabarti S, Sharma Bora N, Mandal S, Pathak MP, et al. Validated RP-HPLC/DAD Method for the Quantification of Insect Repellent Ethyl 2-Aminobenzoate in Membrane-Moderated Matrix Type Monolithic Polymeric Device. Journal of Chromatographic Science. 2017;55(6):645–53. (IF: 1.5)

2014:

50. Mazumder S, Pathak M. Acute And 28-Day Repeated Dose Toxicity Of Averrhoa Carambola Leaves Ethanolic Extract In Rodents. International Journal of Pharma Sciences and Research. 2014;5(11).

51. Chattopadhyay P, Banerjee S, Pathak MP, Agnihotri A, Karmakar S, Goyary D, et al. Acute and subchronic dermal toxicity of Vitex negundo essential oil. Cutaneous and Ocular Toxicology. 2014;33(1):16–21. (IF: 1.6)

52. Pompy Patowary, Roy K, Barua CC, Pathak MP, Haloi P. Influence of Acetaminophen on serotonergic mediated behaviors in mice. Journal Of Veterinary Pharmacology And Toxicology. 2014. 14, pp.49-54.

53. Banerjee S, Chattopadhyay P, Ghosh A, Pathak MP, Gogoi J, Veer V. Protection by a transdermal patch containing eserine and pralidoxime chloride for prophylaxis against (±)-Anatoxin A poisoning in rats. European Journal of Pharmaceutical Science. 2014;56:28–36. (IF: 4.3)

2013:

54. Banerjee S, Chattopadhyay P, Ghosh A, Pathak MP, Singh S, Veer V. Acute Dermal Irritation, Sensitization, and Acute Toxicity Studies of a Transdermal Patch for Prophylaxis Against (±) Anatoxin-A Poisoning. International Journal of Toxicology. 2013;32(4):308–13. (IF: 1.2)

Book Chapter:

 

2024:

  1. Das, A., Pathak, K., Pathak, MP., Gogoi, U.,  and Saikia, R. 2024. Lyme Disease Management: Antibiotics and Beyond in SK Amponsah, R Shegokar and YV Pathak (eds), Rising Contageous Diseases, Basic Management and Treatments. 1st Edition. Wiley.

2023:

  1. Das, A; Pathak, K; Pathak, MP; Gogoi, U; Saikia, R. and Acharya, NS. 2023. Potential of Herbal platforms drug delivery in treating Malaria in  R Shegokar, Y Pathak (eds), Malaria and Drug Delivery Systems,1st edition, Springer.
  2. Das, A; Pathak, K; Pathak, MP; Gogoi, U. and Saikia, R. 2023. NRF2 The aging liver in KFA Soliman and Y Pathak (eds), Flavonoids and Anti-Aging: Activation of The Transcription Factor Nuclear Erythroid 2-Related Factor2. 1st edition, CRC Press.
  3. Das, A; Pathak, MP; Pathak, K; Gogoi, U. and Saikia, R. 2023. Changes in the regulation of energy metabolism in chronic diseases using functional foods and Nutraceuticals in S Mohan, S Abdollahi, Y V Pathak (eds),  Application of Functional Foods and Nutraceuticals for Chronic Diseases. 1st edition, CRC Press.

2021

  1. Pathak, K; Gogoi, U; Pathak, MP; Saikia, R. and Das, A. 2021. Modified Marine Antidiabetics: An insight into their sources, chemistry, SAR and molecular mechanisms in A.U. Rahman (ed), Studies in “Natural Product Chemistry (Bioactive Natural Products)” Elsevier Science.
  2. Das, A; Pathak, MP; Patowary, P. and Das, S. 2021. ‘Introduction to physiology of lung from drug delivery perspective’ in Y Pathak & N Islam (eds), Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences. CRC Press
  3. Patowary, P; Pathak, MP; Chattopadhyay, P; Zaman, K. 2021. ‘vascript:__doPostBack('gvBookDetails$ctl20$lbtnChapterTitle','')">Nanomedicine for the Management of Pulmonary Disorders’ in Y Pathak & N Islam (eds), Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences. CRC Press
  4. Pathak, K; Pathak, MP; Gogoi, U; Saikia, R. and Das, A. 2021. COVID19: Preventive and Protective Control Management Strategies’, Coronaviruses. Bentham Science, 2021, Vol. 02

2020

  1. Das, A; Saikia, R., Pathak, K., Gogoi, U. and Pathak, M.P. 2020. ‘Anti-diabetic Nano-formulation from Herbal Source’ in MK Das & Y Pathak (eds), Nano Medicine and Nano Safety-Recent Trends and Clinical Evidences. Springer Nature Singapore Pvt. Ltd.
  2. Das, A; Pathak, K., Pathak, M.P., Chattopadhyay, P., Saikia, R., Sahu, S. and Gogoi, U. 2020. ‘Enzyme Inhibition’ in C. Singhla (ed), Recent Advances in Pharmaceutical Sciences (Vol-3). AkiNik Publications.

2019:

  1. Bora, SN., Mazumder, B., Pathak, M.P. and Joshi, K. 2019. ‘Nanotechnology in Preventive and Emergency Healthcare’ in B. Mazumder, S Ray, P Pal & Y Pathak (eds), Nanotechnology: Therapeutic, Nutraceutical, and Cosmetic Advances, CRC Press.

2017:

Das, A., Pathak, M.P., Chattopadhyay, P. and Pathak, Y.V. 2017. ‘Gene-Based Dietary Advice and Eating Behavior’ in Y.V. Pathak & A.M. Ardekani, (eds), Nutrigenomics and Nutraceuticals: Clinical Relevance and Disease Prevention, CRC Press.

Awards & Achievements

Fellowships/Awards/Honours Authority/Institution
Best Researcher Award Assam down town University. Assam. India. (2022, 2023, 2024)
Faculty of the Month Assam down town University. Assam. India. (April 2022, May 2023, May 2024)
CSIR Foreign Travel Grant CSIR. New Delhi. India. (2018)
Congress Bursary Award WCP2018.  Kyoto. Japan. (2018)
Senior Research Fellow University Grant Commission, New Delhi, India (2017-20)
Junior Research Fellow University Grant Commission, New Delhi, India (2013-14)
GPAT (Graduate Pharmacy Aptitude Test) Conducted by AICTE, New Delhi (2013)
Postgraduate Scholarship (PGSPROF) University Grant Commission, New Delhi, India (2011-12)