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MPharm(Pharmacology)

2 Years Master Degree Programme

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Programme Details

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2 Years Programme

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Presently, FPS AdtU offers M. Pharm programmes in Pharmaceutics and Pharmacology. These programmes were established to fulfil the need for specialized knowledge in the NER region and to encourage graduates to continue their higher studies. A key objective of offering the M. Pharm programmes was to drive ongoing research activities by involving postgraduate students. As a result, postgraduate students have opportunities to advance their studies to the PhD level and select a career that aligns with their passions.

Curriculum Details

Year wise Course Details

Odd Semester

Courses for this semester

Course Overview

The subject imparts a fundamental knowledge on the structure and functions of cellular components and help to understand the interaction of these components with drugs. This information will further help the student to apply the knowledge in drug discovery process.

Course Outcomes

  • Explain various cellular events, functions, pathways and transduction mechanisms and how a gene is expressed.
  • Cell signaling pathways based on receptors and second messengers in the cell.
  • Principles and applications of genomic, proteomic tools, gene therapy and rDNA technology.
  • Immunotherapeutic and application of omics in clinical practice.
  • Principles and applications of various assays, biosimilars, cell culture techniques, application of flowcytometry.

Course Overview

This subject deals with various advanced analytical instrumental techniques for identification, characterization and quantification of drugs. Instruments dealt are NMR, Mass spectrometer, IR, HPLC, GC etc

Course Outcomes

  • Remembering the theory instrumentation and applications of UV-Visible Spectroscopy, IR Spectroscopy ,Spectroflourimetry & Flame Photometry.
  • Students will learn the acquired knowledge from NMR spectroscopy for interpretation of compounds and their structural identification of molecules.
  • Student will Identify the molecular structure and confirming whether the molecule consists of ring structure or chain compounds and also in structural elucidation by Mass spectroscopy
  • Analyzing the basic principle, instrumentation chromatographic parameters, factor affecting resolution and applications of chromatography
  • Student will gain the knowledge about different analytical techniques for their applicability by Electrophoresis, X-ray diffraction, RIA and ELISA

Course Overview

The course is designed to strengthen the basic knowledge in the field of pharmacology and to impart recent advances in the drugs used for the treatment of various diseases. In addition, this subject helps the students to understand the concepts of drug action and mechanisms involved

Course Outcomes

  • Appreciate the basic knowledge in the field of pharmacology pertaining to the drugs and its therapeutic applications.
  • Elaborately learnt the recent advances in the drugs used for the treatment of various diseases.
  • Understood the concepts of drug action and mechanisms involved.
  • Understood the underlying mechanism of drug actions at cellular and molecular level.
  • Learn the adverse effects, contraindications and clinical uses of drugs used in treatment of diseases.

Course Overview

This subject deals with identification, characterization, separation and quantification as well identifying and quantifying the impurities by using the instruments such as U.V, I.R, Spectrofluorimetry, Flame Emission spectroscopy, Atomic Absorption spectroscopy, N.M.R, Mass, Chromatography, Electrophoresis, X-Ray crystallography, RIA and ELISA.

Course Outcomes

  • Recall and Classify fundamental principles and theories of various pharmaceutical analytical techniques.
  • Summarize and Plan theoretical basis behind different analytical techniques and their suitability for specific applications.
  • Apply and Establish the knowledge of pharmaceutical analytical techniques to select appropriate methods for specific drug analysis scenarios.
  • Analyze and Interpret complex data sets obtained from various pharmaceutical analytical techniques.
  • Design and develop analytical methods for the quantification and characterization of pharmaceutical compounds.

Course Overview

This subject imparts knowledge on the good laboratory practices to handle the animals for use in various disease models for pharmacological evaluation of drugs & new chemical entities. This knowledge will make the student competent in various in-vivo and in-vitro assays as part of the pre-clinical drug evaluation and to correlate the preclinical data to humans.

Course Outcomes

  • Discuss different aspects like description, handling, production, maintenance and application of different common laboratory and transgenic animal models to be used in pharmacological as well as toxicological screening of drugs and new chemical entities.
  • Explain preclinical screening of new substances in different animal as well as in in-vitro and other possible animal alternative models related to central and autonomic nervous system diseases like Parkinsonism, Alzheimer's and multiple sclerosis.
  • Define and explain preclinical screening of new substances in different animal as well as in in-vitro and other possible animal alternative models related to respiratory, reproductive, inflammatory and digestive system diseases like asthma, COPD, infertility, inflammation, fever, ulcer, emesis and diarrhea.
  • Discuss the preclinical screening of new substances in different animal as well as well as in in-vitro and other possible animal alternative models related to cardiovascular, endocrine, immune and digestive system diseases like hypertension, arrhythmia, angina pectoris, atherosclerosis, diabetes, dyslipidemia, cancer and hepatotoxicity.
  • Define and explain preclinical screening of new substances like immunomodulators, immunosuppressants and immunostimulants by various immunoassays conducted in different animal as well as in in-vitro and other possible animal alternative models.

Course Overview

The course "Modern Pharmaceutics" in the Master of Pharmacy (M. Pharm) program, as per the Pharmacy Council of India (PCI) syllabus, is designed to provide in-depth knowledge and understanding of contemporary pharmaceutical formulation development and drug delivery systems. This course aims to equip students gain the necessary knowledge about pre-formulation concept, Optimization techniques in Pharmaceutical Formulation, Validation, cGMP & Industrial Management, Compression and compaction and Study of consolidation parameters.

Course Outcomes

  • The elements of pre-formulation studies.
  • The Active Pharmaceutical Ingredients and Generic drug Product development
  • Industrial Management and cGMP Considerations.
  • Optimization Techniques & Pilot Plant Scale Up Techniques
  • Stability Testing, sterilization process & packaging of dosage forms.

Course Overview

The subject imparts a fundamental knowledge on the structure and functions of cellular components and help to understand the interaction of these components with drugs. This information will further help the student to apply the knowledge in drug discovery process.

Course Outcomes

  • Understand the basic knowledge in the field of pharmacology.
  • Demonstrate and impart recent advances in the drugs used for the treatment of various diseases.
  • Demonstrate the concepts of drug action and mechanisms involved, and understand the adverse effects.
  • Explain the contraindications and clinical uses of drugs and the mechanism of drug actions at the cellular and molecular levels.
  • Discuss the pathophysiology and pharmacotherapy of diseases.

Course Overview

The Drug Delivery Systems course is designed to provide an in-depth understanding of various drug delivery technologies, mechanisms, and approaches used in the pharmaceutical industry. The course will cover the principles, design, and evaluation of different drug delivery systems, including conventional and advanced delivery methods. Students will explore how drug delivery systems can improve drug efficacy, bioavailability, and patient compliance. Additionally, the course will focus on recent advancements and emerging trends in drug delivery research.

Course Outcomes

  • Describe the fundamental concepts and theories of drug delivery systems
  • Explain the principles of drug release kinetics and drug transport across biological barriers.
  • Evaluate the advantages and limitations of various drug delivery systems, including oral, transdermal, parenteral, and pulmonary routes.
  • Analyze the role of nanotechnology and biomaterials in drug delivery applications and Understand the regulatory considerations and challenges associated with the development of drug delivery systems.
  • Identify recent advancements in drug delivery research and their potential impact on the pharmaceutical industry.

Course Overview

These outcome points can serve as the basis for structuring a comprehensive training or presentation on the intricate processes involved in drug development and regulatory affairs. Each point can be expanded upon with specific examples and case studies to provide a deeper understanding of the subject matters.

Course Outcomes

  • Concepts of innovator and generic pharmaceuticals, as well as the drug development process
  • Understanding guidelines and regulatory advice for the filing and approval procedure.
  • Various dossiers are prepared and submitted to regulatory bodies in various nations
  • Understand Post-approval regulatory procedures for active ingredients and pharmaceutical products. Global document submission in CTD/eCTD formats
  • Understand the Clinical trial approval criteria for conducting clinical trials

Course Overview

In an M.Pharm program with a focus on Pharmaceutics, students engage in a multifaceted learning experience. This includes conducting in-depth literature reviews to grasp the latest developments in pharmaceutical research, designing and executing experiments related to drug formulation and delivery systems, analyzing real-world pharmaceutical cases to propose practical solutions, and participating in collaborative drug development projects aimed at creating new pharmaceutical products. Additionally, students gain valuable insights into regulatory compliance by researching and presenting on pharmaceutical regulations and quality control standards. Communication skills are honed through the effective presentation and written communication of complex pharmaceutical concepts, preparing students for success in the dynamic field of pharmaceutics.

Course Outcomes

  • Recall and summarize key pharmaceutical concepts.
  • Explain the principles underlying drug formulation and Interpret data from pharmaceutical experiments.
  • Demonstrate the application of pharmaceutical knowledge to solve practical problems and Utilize pharmaceutical software or tools for drug formulation or analysis.
  • Analyze research data to draw conclusions about pharmaceutical processes and Evaluate the effectiveness of different drug delivery systems.
  • Evaluate the quality control measures in pharmaceutical manufacturing and Design novel drug formulations based on research findings.

Course Overview

Pharmaceutics is the study of how drugs work and how they may be made. Each stage in the production of a completed dosage form has the potential to alter the rate at which the drug is released from the drug product and the concentration of the drug at the site of action. Both experimental and theoretical methods are used in the study of pharmacokinetics. Developing analytical methods for the measurement of medicines and metabolites, as well as processes that simplify data collection and processing, are all part of the experimental element of pharmacokinetics.

Course Outcomes

  • The fundamental ideas in quantitative research and pharmacokinetics
  • The method of determining the amount of a medicine using a UV viscible spectrophotometer is best described as.
  • Conduct an in-depth analysis of the pharmaceutical drug release studies that are part of the medication product development process.
  • The formulation and analysis of dosing regimens for the medications, taking into account pharmacokinetic and Bio-pharmaceutic factors.
  • The possible clinical pharmacokinetic difficulties as well as the use of the different dose forms.

Course Overview

M.Pharm program with a focus on Pharmacology, students engage in a multifaceted learning experience. This includes conducting in-depth literature reviews to grasp the latest developments in pharmaceutical research, designing and executing experiments related to drug formulation and delivery systems, analyzing real-world pharmaceutical cases to propose practical solutions, and participating in collaborative drug development projects aimed at creating new pharmaceutical products. Additionally, students gain valuable insights into regulatory compliance by researching and presenting on pharmaceutical regulations and quality control standards. Communication skills are honed through the effective presentation and written communication of complex pharmaceutical concepts, preparing students for success in the dynamic field of pharmacology.

Course Outcomes

  • Recall and summarize key pharmacological concepts.
  • Explain the principles underlying mechanism of drugs and interpret data from pharmacological experiments.
  • Demonstrate the application of pharmacological knowledge to solve practical problems
  • Analyze research data to draw conclusions about pharmacological aspects.
  • Scientific communication skill will be enriched
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Even Semester

Courses for this semester

Course Overview

This course covers the conception of innovative drug delivery systems using several methodologies, as well as the selection of medicines and polymers for NTDS development, formulation, and assessment.

Course Outcomes

  • Design drug delivery systems for targeting drugs to tumours and to the brain
  • Prepare and evaluate nanoparticles and liposomes as carriers for drug targeting
  • Select drugs and polymers in the design of microspheres and microcapsules for various applications
  • Formulate aquasomes, niosomes, phytosomes and electrosomes for various applications in drug targeting
  • Optimize pulmonary delivery by the design of suitable aerosols, nebulizers and dry powder inhalers and develop strategies for the design of nasal drug delivery systems and Apply gene therapy in the treatment of cancer and inherited diseases

Course Overview

This course aims to provide students with an understanding of the process of drug discovery and development from the identification of novel drug targets to the introduction of new drugs into clinical practice. It covers the basic principles of how new drugs are discovered with emphasis on lead identification, lead optimization, classification and kinetics of molecules targeting enzymes and receptors, prodrug design and applications, as well as structure-based drug design methods. Recent advances in the use of computational and combinatorial chemistry in drug design will also be presented. The course is further enhanced with invited lectures on recent developments and applications of drug design principles in the pharmaceutical industry.

Course Outcomes

  • Student will able to understand the various stages of drug discovery
  • Student will able to explain various lead seeking method and lead optimization
  • To appreciate the importance of the role of genomics, proteomics and bioinformatics in drug discovery
  • Student will able to explain various targets for drug discovery.
  • To understand the importance of the role of computer aided drug design in drug discovery

Course Overview

The goal of the course "Computer Applications in Pharmaceutical Research and Development" is to teach students the fundamentals of computer science and how they are used to the whole process of creating new pharmaceuticals.

Course Outcomes

  • Understand the Computers in Pharmaceutical Research and Development.
  • Utilize the knowledge for Computational Modeling Of Drug Disposition
  • Understand the Computer-aided formulation development
  • Understand the scope of Computer-aided Pharmacokinetics and Pharmacodynamics characterization
  • Understand and summarize the general Artificial Intelligence (AI), Robotics and Computational fluid dynamics

Course Overview

The course covers the regulatory requirements for conducting a clinical trial, and different types of clinical trials including the responsibilities of key players involved in clinical trials as well as documentation requirements for clinical trials. Moreover, it covers Adverse drug reactions and their management and ADR reporting, methods and tools used in Pharmacovigilance. It will give basic information on Pharmacoepidemiology, pharmacoeconomics and safety pharmacology.

Course Outcomes

  • Student will strengthen the basic knowledge in the field of clinical research and pharmacovigilance.
  • Student will strengthen the basic knowledge in the field of clinical research and pharmacovigilance.
  • Student will be able to appreciate the responsibilities key personnel involved in clinical trials and execute safety monitoring, reporting and close-out activities.
  • Student will able to explain the principles of Pharmacovigilance, detect new adverse drug reaction and their assessment and perform the adverse drug reaction, reporting systems and communication in Pharmacovigilance.
  • Describe Pharmacoepidemiology, pharmacoeconomics and safety pharmacology.

Course Overview

The course explore into both foundational and advanced pharmacological aspects, facilitating an understanding of disease pathophysiology, drug classifications, mechanisms of action, adverse effects, contraindications, and interactions. It also provides insights into recent advancements in drug therapy for diverse diseases, emphasizing the molecular basis of drug effects to ensure their safe and effective utilization.

Course Outcomes

  • Demonstrate an understanding of the mechanism of action of different hormones and associated drugs at the cellular and molecular levels.
  • Explain the mechanism of action and adverse drug reactions associated with drugs used in protozoal infections, helminthiasis, and various antimicrobial agents, including antifungal, antiviral, and anti-TB drugs, on a cellular and molecular level as well as analyze the development of drug resistance.
  • Apply knowledge to elucidate the pathophysiology, therapy, and adverse drug reactions of drugs used in cancer, inflammation, allergy, asthma, and COPD as well as understand the principles behind immunosuppressants and immunostimulants.
  • Analyze the pathophysiology, therapy, and adverse drug reactions of antiulcer drugs, prokinetics, antiemetics, anti-diarrheals, and drugs for constipation and irritable bowel syndrome and to evaluate the applications of chronotherapy in various diseases.
  • Correlate the role of free radical generation with the etiology of various diseases and understand the importance of the protective activity of antioxidants as well as synthesize knowledge on recent advances in the treatment of neurodegenerative diseases, cancer, and diabetes.

Course Overview

This course introduces the fundamental principles and practices of toxicology, including dose-response and toxicokinetic analysis. It will also cover reproductive toxicology, Toxicokinetic evaluation in preclinical studies. IND enabling studies (IND studies) emphasize understanding mechanisms for these responses.

Course Outcomes

  • Define the basics of toxicology as well as good laboratory practice and discuss the role of various toxicology regulatory agencies.
  • Discuss and apply various guidelines by regulatory agencies to conduct toxicological assays in oral, dermal, and inhalation routes.
  • Discuss and apply various guidelines by regulatory agencies to conduct reproductive and genotoxicity assays in in-vivo and in-vitro setups.
  • Explain and evaluate various aspects of investigational new drugs and safety pharmacology studies.
  • Define toxicokinetics and alternative methods to animal toxicity testing and analyze their role in drug development.

Course Overview

Bio-pharmaceutics provides the scientific basis for drug product design and drug product development. Each step in the manufacturing process of a finished dosage form may potentially affect the release of the drug from the drug product and the availability of the drug at the site of action. The study of pharmacokinetics involves both experimental and theoretical approaches. The experimental aspect of pharmacokinetics involves the development of biologic sampling techniques, analytical methods for the measurement of drugs and metabolites, and procedures that facilitate data collection and manipulation.

Course Outcomes

  • Explain mechanism of drug absorption &various factors affecting drug absorption and Learn various Bio pharmaceutics factors affecting drug bioavailability.
  • Understand and Apply various method of dissolution testing. In vitro–In vivo correlation dissolution data and elaborate design Bioavailability and Bioequivalence studies of new drugs or dosage forms
  • Understand basic considerations of pharmacokinetic models. Understand different compartment model and non-compartment model
  • Explain the design and evaluation of dosage regimens of the drugs using pharmacokinetic and Bio pharmaceutics parameters and also Study the application
  • Understand the different types of drug interactions which alter the pharmacokinetics of such as drug-protein /drug-tissue binding interactions

Course Overview

Cosmetics and cosmeceutical science is a master's degree program in pharmacy that focuses on the combination of cosmetics and pharmaceuticals, as well as various building blocks. Cosmeceutical science is a relatively new field that arose as a result of today's generation's high demand for cosmetics and beauty care products. Cosmetics just manage skin's surface issues; cosmeceuticals address the underlying causes of skin problems and produce long-lasting effects. Cosmetics produce results immediately and instantly, but cosmeceuticals produce benefits gradually but permanently. The experts advise avoiding using cosmetics. Cosmeceuticals are always advised by dermatologists and skincare specialists.

Course Outcomes

  • Describe the regulatory provisions related to the import and manufacture of cosmetics as per the Drugs and Cosmetics Act 1940 and the Rules 1945
  • Explain the various problems related to the skin and hair
  • Design cosmetics that take care of cleansing needs of the face, eye lids, lips, hands, feet, nail, scalp, neck, body and under-arm
  • Design cosmetics and cosmeceuticals with desired safety, stability and efficacy with a knowledge of the various technologies involved in their manufacture
  • Design cosmetics for sun protection, dry skin, acne, sun-protection, pigmentation, prickly heat, wrinkles, and body odor. Dandruff, dental cavities, bleeding gums, mouth odor and sensitive teeth.

Course Overview

Bio-pharmaceutics provides the scientific basis for drug product design and drug product development. Each step in the manufacturing process of a finished dosage form may potentially affect the release of the drug from the drug product and the availability of the drug at the site of action. The study of pharmacokinetics involves both experimental and theoretical approaches. The experimental aspect of pharmacokinetics involves the development of biologic sampling techniques, analytical methods for the measurement of drugs and metabolites, and procedures that facilitate data collection and manipulation.

Course Outcomes

  • Students will able to formulate different dosage forms
  • Students will understand the methods and apply the skills as well as knowledge for the Development of the novel drug delivery systems.
  • Students will apply the knowledge to find the causes and analyze the procedures to solve the practical problems in the designing of new dosage forms
  • Students will compare the outcome results by following various set of procedures and simplify the Disputes, for the optimization of novel pharmaceutical product development
  • Students will develop the new procedure or method after analyzing and simplifying the results

Course Overview

Pharmacology Practical-II – Involves the study of all about drugs, what drugs do to living organisms and how their effects can be applied to therapeutics. This subject caters in-depth knowledge on handling various equipment and developing animal models for screening, the molecular and cellular mechanism of action, deficiency and excess release related endocrine disorders, alternative methods for animal toxicity testing employed in drug discovery and development, and various targets for drug discovery, various lead-seeking methods and lead optimization, designing different protocols, regulations and ethical requirements for the usage of experimental animals.

Course Outcomes

  • Evaluate the efficacy and potency of different drugs in isolated animal tissues with the help of bioassays.
  • Estimate the toxicity profile of drugs in different routes of administration by following the guidelines laid down by various regulatory agencies.
  • Assess the effect and potency of different drugs on blood pressure, heart rate, and ECG using in vivo models.
  • Demonstration on how to design a protocol for clinical trials and monitoring of adverse drug reactions.
  • Discuss and demonstrate the in-silico techniques for the prediction of drug targets and drug-like molecules.
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Odd Semester

Courses for this semester

Course Overview

Research Methodology & Biostatistics deals with descriptive statistics, Graphics, Correlation, Regression, logistic regression Probability theory, Sampling technique, Parametric tests, Non Parametric tests, ANOVA, Introduction to Design of Experiments, Phases of Clinical trials and Observational and Experimental studies, analyzing the statistical data using Excel.

Course Outcomes

  • Analyze the value, scope, objectives and requirements of research
  • Discuss the basic concepts of statistical analysis.
  • Apply the basic principles of medical research and ethics.
  • Understand the guidelines for the maintenance of laboratory animals and design research work.
  • Create efficiency in solving practical difficulties.

Course Overview

The Journal Club course in a Pharmaceutics master's degree program is designed to enhance students' critical thinking, research analysis, and communication skills. This course focuses on reviewing and discussing current research articles, publications, and studies related to pharmaceutical sciences, drug development, and other relevant topics.

Course Outcomes

  • Students will be able to critically evaluate research articles by identifying the research question, methods, results, and implications.
  • Students will improve their ability to present scientific information effectively, both orally and in written form, fostering clear and concise communication of complex research findings.
  • Develop skills in efficiently searching, retrieving, and organizing scientific literature, enabling them to stay current with the latest research in Pharmaceutics.
  • Engage in informed and constructive discussions and debates about various research topics, demonstrating the ability to articulate and defend their viewpoints based on scientific evidence.
  • Demonstrate the ability to work collaboratively with peers in analyzing and presenting research articles, fostering a cooperative learning environment.
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Even Semester

Courses for this semester

Course Overview

The Journal Club course in a Pharmaceutics master's degree program is designed to enhance students' critical thinking, research analysis, and communication skills. This course focuses on reviewing and discussing current research articles, publications, and studies related to pharmaceutical sciences, drug development, and other relevant topics.

Course Outcomes

  • Students will be able to critically evaluate research articles by identifying the research question, methods, results, and implications. They will assess the quality and validity of the research presented.
  • Students will improve their ability to present scientific information effectively, both orally and in written form, fostering clear and concise communication of complex research findings.
  • Develop skills in efficiently searching, retrieving, and organizing scientific literature, enabling them to stay current with the latest research in Pharmaceutics.
  • Engage in informed and constructive discussions and debates about various research topics, demonstrating the ability to articulate and defend their viewpoints based on scientific evidence.
  • Demonstrate the ability to work collaboratively with peers in analyzing and presenting research articles, fostering a cooperative learning environment.
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Scholarship

Apply Scholarship through CST

CST- Common scholarship test is a national and international level online MCQ based examination funded for intellectual empowerment by Assam down town University.

CST- Maximum enrolment each year is 120 seats and any 10+2 students can apply. Adtu is northeast India’s first placement driven university to provide 100% scholarship benefits worth 10 cr.

CST aims to inspire brilliant and competent students to pursue further education. Accredited with a prestigious grade by NAAC, UGC and AICTE.

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A 50% scholarship on total semester fees is provided to all specially abled students.

A 100% scholarship on the last semester fee is provided to all the alumni of Assam down town University.

A 100% scholarship on total semester fee for Economically Backward Classes

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MPharm(Pharmaceutics)
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