Dr. Rajeev Sarmah

COMPUTATIONAL SKILLS

• Programming languages : C, Java(Core), Visual Basic6.0,  Perl 
• BioProgramming : Bioperl, Biojava.
• Operating System familiar to : Unix, Linux, Windows 98/2000/XP/NT
• Database : Oracle 8i, MS Access
• Application Software : MS Office
• Bioinformatics Softwares : 
• Data Mining Tools : BLAST, FASTA, VAST, CE, DALI
• Multiple Sequence Alignment  : CLUSTALw, CLUSTALx
• Phylogenetic Analysis tools : Phylip Package, MEGA
• Sequence Editing  : BioEdit 
• Protein Molecule viewing  : RASMOL, Cn3D, VMD
• Protein Modeling   : Modeler.
• Docking and MD Simulation : Autodock, Gromacs

Research Publications:

1. S Sinha, S Mali, U Borgohain, U Saikia, G Chetia, SP Medhi, D Borthakur, J. Aich, G. Mukerjee, D. Ghosh, R. Sarmah. "A Machine Learning Approach for Detection and Classification of Colon Cancer using Convolutional Neural Network Architecture." J. Electrical Systems 20, no. 7s (2024): 1065-1071.
2. Loying, Surjya, Rajeev Sarmah, Manash Pratim Sarma, Abdul Malik, Suhail Akhtar, Azmat Ali Khan, Rahul Nayak, and Devabrata Saikia. "Essential oils ofáindigenous citrus varieties ofáNortheast India asápotential antibiofilm agents against foodborne pathogens: Anáinávitro and inásilico study." Czech Journal of Food Sciences (2024).
3. Khan, Reyaz Ahmad, Kangjam Rekha Devi, Manash Pratim Barman, Madhusmita Bhagawati, and Rajeev Sarmah. "Bacteria in the oral cavity of individuals consuming intoxicating substances." Plos one 18, no. 5 (2023): e0285753.
4. Khan, Reyaz Ahmad; Sarmah, Rajeev. Factors influencing microbial growth in the human oral cavity. Reviews and Research in Medical Microbiology 34(3):p 123-129, July 2023. | DOI: 10.1097/MRM.0000000000000338
5. Sarmah, Rajeev, and Anjan Kumar Sarma. "Phosphate solubilizing microorganisms: A review." Communications in Soil Science and Plant Analysis 54, no. 10 (2023): 1306-1315.
6. M.H. Khandakar, S. Loying, R. Sarmah, D. Saikia, H. C. Singh and M.P. Sarma “Essential Oil and Cancer Cells: A Review”. Indian Journal of Natural Sciences 13, no. 72, (2022) 43064-43071
7. Rajeev Sarmah, Debo Kanta Pegu, Madhusmita Bhagawati, “Search for target proteins og Helicobacter pilori and modelling”. AMRIT, 1(2), (2022), 48-54
8. Kalita, Partha Pratim, Manabendra Nayak, Manash Pratim Kashyap, Rajeev Sarmah, and Manash Pratim Sarma. "A SNP Study Of HSP Gene And Its Protein Modelling In Liver Disease Cases From North East India." Uttar Pradesh Journal of Zoology 42, no. 17 (2021): 62-73.
9. Sarmah, Rajeev, Reyaz A. Khan, and Kangjam R. Devi. "Microbes in human oral cavity: a review." Reviews in Medical Microbiology 32, no. 2 (2021): 75-82.
10. Saikia, Surovi, Manobjyoti Bordoloi, Rajeev Sarmah, and Bhaskor Kolita. "Antiviral compound screening, peptide designing, and protein network construction of influenza a virus (strain a/Puerto Rico/8/1934 H1N1)." Drug development research 80, no. 1 (2019): 106-124.
11. Bhagawati, Madhusmita, Naba Kanka Hazarika, Mrinal Kumar Baishya, Kandarpa Saikia, Devo Kanta Pegu, and Rajeev Sarmah. "Effect of Centella Asiatica Extracts on Shigella Dysenteriae and Bacillus coagulans Compared to Commonly Used Antibiotics."
12. Gohain, Anwesha, Rupak Kumar Sarma, Rajal Debnath, Juthika Saikia, Bhim Pratap Singh, Rajeev Sarmah, and Ratul Saikia. "Phylogenetic affiliation and antimicrobial effects of endophytic actinobacteria associated with medicinal plants: prevalence of polyketide synthase type II in antimicrobial strains." Folia microbiologica (2019): 1-16.
13. Bordoloi, Manobjyoti, Surovi Saikia, Bhaskor Kolita, Rajeev Sarmah, Sonali Roy, and Bardwi Narzary. "Volatile Inhibitors of Phosphatidylinositol-3-Kinase (PI3K) Pathway: Anticancer Potential of Aroma Compounds of Plant Essential Oils." Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents) 18, no. 1 (2018): 87-109.
14. Gogoi, Dipshikha, Tazid Ali, and Rajeev Sarmah. "ANALYSIS OF HELICOBACTER PYLORI STRAIN 26695 PROTEOME FOR PROBABLE TARGETS." (2018).
15. Gohain, Anwesha, Animesh Gogoi, Rajal Debnath, Archana Yadav, Bhim P. Singh, Vijai K. Gupta, Rajeev Sharma, and Ratul Saikia. "Antimicrobial biosynthetic potential and genetic diversity of endophytic actinomycetes associated with medicinal plants." FEMS microbiology letters 362, no. 19 (2015): fnv158.
16. Deka, H., Sarmah, R., Sharma, A., & Biswas, S. Modeling and Characterization of Glial Fibrillary Acidic Protein. Vol 11(8) 393-400 2015
17. Jugal Gogoi, Tazid Ali and Rajeev Sarmah  Stochastic Model for Genetic Recombination because of Crossing over and Chromatid Exchange International Journal of Computer Applications (0975 – 8887) Volume 80 – No 13 pp 1 – 3 (2013).
18. Sarmah R. Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone. Bioinformation 8(20): 963-969 (2012). PP 963 – 8. ISSN 0973-2063 PMID: 23275688 PMCID: PMC3524948. doi: 10.6026/97320630008963. http://www.ncbi.nlm.nih.gov/pubmed/23275688.
19. Gogoi. D, Bezbaruah. L.R, Bordoloi M, Sarmah R., Bora T.C. Insights from the docking analysis of biologically active compounds from plant Litsea Genus as potential COX-2 inhibitors. Bioinformation 8(16): 812-815 (2012) PP 812 – 5. ISSN 0973-2063 (online) 0973-8894 (print) PMID: 23139590 PMCID: PMC3488843 doi: 10.6026/97320630008812.
20. Sarmah R. and Kar S. Design and Prediction of Potential siRNAs for PTGS in Three Viruses Causing          Diseases in Rice (Oryza sativa).Journal of Computational Intelligence in Bioinformatics.          Volume 5, Number 2 (2012) pp. 75-84.  ISSN 0973-385X
21. Hazarika R., Borkotoky S., Das B., Sarmah R., Neog B., Evolutionary relationship study of Methyltransferase (O-Methyltransferase, Eugenol O- Methyltransferase, Chavicol O- Methyltransferase and Orcinol O- Methyltransferase) from aromatic medicinal plants. Bulletin of life sciences 03/2012; 18:71-81.
22. Sarmah R., (2011) Arbuscular mycorrhizal fungi: their diversity in lands abandoned due to shifting cultivation. Bull. Life Sci., Vol XVI, 61-72. ISSN 0971-5746.
23. Johari S., Sarmah R., Sinha S., (2011) Ligand Binding Studies for DPP IV a target protein responsible for diabetes mellitus Type 2 : Structural based approach for drug designing , Proceedings of IEEE NCETACS , INSPEC Accession Number: 11945953  ISBN: 978-1-4244-9578-8 .
24. Sarmah. R., (2010): Regeneration of Arbuscular Mycorrhizal Fungi in Soils Distributed by Shifting Cultivation. Bulletin of Life Sciences, XVI 18 – 28. ISSN 0971-5746.
25. Sinha S., Johri S., Sarmah R., (2010). An Extensive Study on Entities and Relationships of cell Line Database (CLDB)- A Proposed Remodelled Schema, Bull. Life Sci. Vol XVI,18. ISSN 0971-5746.
26. Devi, M., Das, B., and Sarmah R., (2003) Phylloplane mycoflora on Cycas and Gnetum. Ad. Plant Sci 16(I)333-335
27. Sarmah R., et al., (2001) Impact of shifting cultivation on the occurrence of Vesicular Arbuscular Mycorrhizal Fungi. J. Adv. Pl.Sc.  pp 56-65 vol 3, ISSN 0971-9350
28. Mazid E., Sarmah R., and Bhattacharjee R., (2001): Comparative study of VAM status of ‘Jhum’ abandoned, natural areas and cultivated land of Karbi Anglong Dist of Assam. J. Adv. Pl.Sc. pp 121-128 vol 3, ISSN 0971-9350
29. Sarmah R. and Mazid E., (2001): VAM in the Rhizosphere of Bambusa bacceifera and B. Arnudinacea. J. Adv. Pl.Sc.2001 pp 103-106 vol 3, ISSN 0971-9350

Seminars, Symposium, Workshops and Trainings

• May'99-Apr'02 – Joined as research fellow for three years in a project entitled “Exploitation of Vecicular Arbuscular Mycorrhizal Fungi for Re-vegetation of Land Degraded due to Shifting Cultivation”, financed by Ministry of Environment and Forests Govt. of India, in the Department      of Botany Cotton College, Guwahati, Assam.
• Mar 1997 – Sep 1997 – Joined as research fellow for six months in a project entitled “Screening         of Free Living Nitrogen Fixing Bacteria and their Cellulolytic and Xylanolytic Activities”. financed by Department of Science and Technology, Govt. of India in the Department of Botany Cotton College, Guwahati Assam. 
• National Workshop on “Microbial Biodiversity Prospecting for PGPRs of N.E. Region for Sustainable Agriculture”, 15th to 19th Oct, 2001, Institute of Advanced Study in Science and Technology (IASST) Guwahati.
• UGC Sponsored National Seminar on Botanical Research in Wildlife Sanctuaries and National Parks of Assam, 27th and 28th July 2002, Handique Girls’ College, Guwahati. Presented paper entitled – “An account of VAM fungal species in Jhum abandoned areas of Karbi Anglong District”.
• DBT sponsored Training on “Applications of Bioinformatics” 13th to 15th Feb 2007, Bioinformatics Centre North East Hill University, Shillong.
• ICMR organised International Symposium on Newer Frontiers in Biomedical research 28th -29th june 2008 venue RMRC-ICMR, Dibrugarh. Presented paper entitled “Sequence similarity pf protein correlates with structural similarity – an analysis”.
• Ministry of Environment and Forests, Govt. of India, CSIR and UGC sponsored National seminar on “Exploration, Utilization and Strategy Action Plan for Sustainable Management of Plant Resources”, 27th and 28th Feb. 2009, Gauhati University, Guwahati. Presented paper entitled “Identification of AM fungi – A computational Approach”.
• Participated UGC sponsored National workshop on Policies and problems of higher education in Assam organized by Handique Girls college, Guwahati in collaboration with Assam college Teachers’ Assocation on 4th and 5th June 2010.
• Participated in the National Conference on Economic Development of Assam organised by Krishna Kanta Handique State Open University, Guwahati on 13th – 15th Dec, 2010.
• Presented Paper “Ligand Binding Studies for DPP IV a target protein responsible for diabetes Mellitus Type 2: Structural based approach for Drug Designing” in the 2nd National Conference on Emerging Trends and Applications in Computer Science held on 4th and 5th Mar, 2011.
• Participated one week National workshop on “Statistical Modelling in Addressing Biological Phenomena” during Feb 25 to Mar 01 2014 organised by Department of Statistics, Dibrugarh University.

 NCBI Submissions

• 78 siRNA Sequences were submitted to NCBI probe database, sequence generated by Rationale Method for siRNA Design. AC_NO – EPM_1: http://www.ncbi.nlm.nih.gov/probe/?term=EPM_1.
• 34 16S rRNA gene sequences of different organisms were submitted to NCBI Nucleotide database, sequences are from bacterial cultures isolated from the oral cavity of individuals from Assam Ac/ No. (OL314722, OL314752, OL314811, OL321134, OL377734, OL347868, OL347880, OL347867, OL347889, OL347894, OL347932, OL348194, OL348271, OL348314, OL348325, OL348370, OL348482, OL351261, OL355135, OL355143, OL355150, OL355152, OL355153, OL374164, OL374166, OL374172, OL375151, OL375152, OL375166, OL375171, OL375175, OL375208, OL375217, OL375218)
• Genome sequence of Kosakonia cawani – JAROAU000000000.1

Research Projects

Completed

“Mathematical Modeling for Evolutionary Biology” Participation as Co-Principal Investigator, In collaboration with Dr. T. Ali, Associate Professor, Department of Mathematics Dibrugarh University, Dibrugarh, Funded by DST, Govt. of India.

Ongoing Projects

“Exploring Nutraceutical Potential of Shiitake (Lentinula edodes) and Maitake (Grifola frondosa) Mushrooms and Promotion of its Production for Entrepreneurial and Socioeconomic Livelihood in North East India” Participation as Principal Investigator, Funded by DBT, Govt. of India. (Completing on 30th March 2024)

“Strengthening of ST community of Anini, Dibang Valley District of Arunachal Pradesh through imparting indigenous knowledge and skills based methods for socio-economic development and sustainable livelihood” Participation as Principal Investigator, To be Funded by DST, Govt. of India.

“STI Hub for Socio-Economic Development Through Hydro-Electric and Solar Power Generation, Integrated Farming and Mushroom Production” Participation as Principal Investigator, To be Funded by DST, Govt. of India

Resource Person

 Ph.D. awarded/ Submitted

Number of students supervising - 06

Scholarships