| Name: | Specialization: |
|---|---|
| Dr. Aparajita Ghosh | LIFE SCIENCE AND NANOTECHNOLOGY |
PhD. (Biotechnology), Indian Institute of Chemical Biology, Kolkata, India (2006-2010) Specialization: Drug Delivery & Nanotechnology.
MSc. (Physiology), University of Calcutta, Kolkata, India (2000-2002).
BSc. (Physiology), Vidyasagar College, University of Calcutta, Kolkata, India (1997-2000).
Feb, 2024-Till Date: Assistant professor cum Research Faculty, Department of Paramedical Science, ADTU, Guwahati
Jan, 2021-Nov, 2023: SERB-Research Associate I, School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India
Dec, 2019-Nov, 2021: Research Associate I, School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India.
Feb, 2019-July, 2019: Scientist C (Contractual), Biochemistry & Drug Discovery Laboratory, Life Science Division, IASST, Guwahati, India.
April, 2018-Jan, 2019: SERB-National Post Doctoral Fellow (Principal Investigator in the project), Department of Biosciences & Bioengineering, IIT, Guwahati, India.
Jan, 2012-Dec, 2016: DBT-Research Associate, Division of Molecular Medicine, Bose Institute, Kolkata, India.
Aug, 2010-Sept, 2011: Research Associate, Molecular Sciences Lab, National Institute of Immunology, New Delhi, India.
1. Ghosh AK, Ghosh A and Das PK. 2024. Nanotechnology Meets Stem Cell Therapy for Treating Glioblastomas: A Review. ACS Appl. Nano Mater. 7: 2430–2460. (IF: 5.9)
2. Ghosh A, Ghosh AK, Zaman A, Das PK. 2023. Metformin - loaded hyaluronic acid-derived carbon dots for targeted therapy against hepatocellular carcinoma by glutamine metabolic reprogramming. Mol. Pharm. doi:10.1021/acs.molpharmaceut.3c00772, Epub ahead of print. PMID: 37933877. (IF: 5.364)
3. Chowdhury M, Pal S, Ghosh A, Das PK.. 2023. Co2+ doped biotinylated carbon dot: A theranostic agent for target specific killing of cancer cells via hypoxia induced apoptosis. Chem. Eur. J. 29: e202300928 (IF: 5.02).
4. Ghosh A, Ghosh AK, Chowdhury M, Das PK. Folic Acid-Functionalized Carbon Dot- Enabled Starvation Therapy in Synergism with Paclitaxel against Breast Cancer. 2022. ACS Appl. Bio Mater. 5: 2389–2402. (IF: 3.25).
5. Kashyap B, Barge SR, Bharadwaj S, Deka B, Rahman S, Ghosh A et al. 2021. Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade. Phytomedicine 93:153761. (IF: 5.34).
6. Barge S, Deka B, Kashyap B, Bharadwaj S, Kandimalla R, Ghosh A et al. 2021. Astragalin mediates the pharmacological effects of Lysimachia candida Lindl on adipogenesis via downregulating PPARG and FKBP51 signalling cascade. Phytotherapy Research. 2021: 1–14. (IF: 5.882).
7. Ghosh A* and Banerjee T. 2020. Nanotized curcumin?benzothiophene conjugate: A potential combination for treatment of cerebral malaria. IUBMB Life. 2020:1-14. (IF: 3.885). (*Corresponding Author).
8. Bhowmik A, Chakravarti S, Ghosh A, Shaw R, Bhandari S, Bhattacharya S, Sen PC, Ghosh MK. 2017. Anti-SSTR2 Peptide based targeted delivery of potent PLGA encapsulated 3,3´- diindolylmethane nanoparticles through blood brain barrier prevents glioma progression. Oncotarget. 8:65339-65358. (IF: 5.168).
9. Bhandary S, Bhowmik A, Ghosh A, Saha S, Pal U, Roy N, Chakraborty N, Chakraborty A, Ghosh M K and Sen P C. 2017. Targeting IL-6/IL-6R Signaling Axis in Triple-Negative Breast Cancer by a Novel Nifetepimine-Loaded Cascade pH Responsive Mesoporous Silica Based Nanoplatform. Global journal of Nanomedicine. 3:1-24.
10. Ghosh A, Bhowmik A, Bhandary S, Putatunda S, Laskar A, Biswas A, Dolui S, Banerjee B, Khan R, Das N, Chakraborty A, Ghosh MK, Sen PC. 2016. Formulation and antitumorigenic activities of nanoencapsulated nifetepimine: A promising approach in treating triple negative breast carcinoma. Nanomedicine: Nanotechnology, Biology and Medicine. 12:1973–1985. (IF: 6.458).
11. Ghosh A, Banerjee T, Bhandary S, Surolia A. 2014. Formulation of nanotized curcumin and demonstration of its antimalarial efficacy. International Journal of Nanomedicine. 9:5373-5387. (IF: 6.4).
12. Mandal A.K., Ghosh D, Sarkar S, Ghosh A, Swarnakar S, Das N. 2014. Nanocapsulated quercetin downregulates rat hepatic MMP-13 and controls diethylnitrosamine-induced carcinoma. Nanomedicine. 9(15):2323-37. (IF: 5.307)
13. Ghosh A, Sarkar S, Mandal A.K. and Das N. 2013. Neuroprotective role of nanoencapsulated quercetin in combating ischemia-reperfusion induced neuronal damage in young and aged rats. PLOS ONE. (DOI: 10.1371/journal.pone.0057735). (IF: 3.04).
14. Ghosh A, Ghosh D, , Sarkar S, Mandal AK, Thakur Choudhury S and Das N. 2012. Anticarcinogenic activity of nanoencapsulated quercetin in combating diethylnitrosamine induced hepatocarcinoma in rats. European Journal of Cancer Prevention. 21(1): 32-41. (IF: 2.497).
15. Ghosh D, Thakur Choudhury S, Ghosh S, Mandal A K, Sarkar S, Ghosh A, Das Saha K, Das N. 2012. Nanocapsulated Curcumin: Oral Chemopreventive Formulation against Diethylnitrosamine induced Hepatocellular Carcinoma in rat. Chemico Biological Interactions. 195: 206-214. (IF: 5.192).
16. Ghosh A and Surolia A. 2011. Gamma-secretase activating protein is a therapeutic target for alzheimer’s disease: A path-breaking discovery finally paving way towards therapeutic intervention. Annals of Neuroscience. 18(1) (SJR:0.588).
17. Ghosh A, Mandal AK, Sarkar S and Das N. 2011. Hepatoprotective and neuroprotective activity of liposomal quercetin in combating chronic arsenic induced oxidative damage in liver and brain of rats. Drug Delivery. 18(6): 451-459. (IF: 6.419).
18. Ghosh D, Ghosh S, Sarkar S, Ghosh A, Mandal AK, Das Saha K and Das N. 2010. Quercetin in vesicular delivery systems: Evaluation in combating arsenic-induced acute liver toxicity associated gene ex
19. Ghosh A, Mandal AK, Sarkar S, Panda S and Das N. 2009. Nanoencapsulation of Quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of rats. Life Sciences. 84, 75-80. (IF: 5.037).
20. Das S, Mandal AK, Ghosh A, Panda S, Das N and Sarkar S. 2008. Nanoparticulated Quercetin in combating age related cerebral oxidative injury. Current Aging Science. 1, 169-174. (IF: 1.78)
Das N, Mandal AK, Sarkar S and Ghosh A. 2007. Liposomal flavonoid in combating age related cerebral oxidative damage. “Biotechnology Applications”. In Book edited by Dr Pascale Champagne of Queens University, Ontario, Canada.
1. Sen PC, Ghosh A, Bhandary S. Anti-Cancer Nifetepimine Nanoformulation. (Patent No. 389777; Application No. 858/KOL/2015)
1. Kashyap B, Bharadwaj S, Barge S, Deka B, Sheikh Y, Rahman S, Ghosh A et al. A Herbal Composition from Premna Herbacea, useful For Prevention of Obesity And Type 2 Diabetes and A Method for its Extraction. (WO 2020/115767 A1, 2020).
2. Barge SR, Kashyp B, Deka B, Bharadwaj S, Saikia S, Kandimalla R, Dutta PP, Hazarika A, Ghosh A et al. A herbal extract from Lysimachia candida for treatment of obesity and related hyperglycemia and a method for its extraction. (Application No. 201931019887 A, 2019).