Dr. Aparajita Ghosh

Dr. Aparajita Ghosh

About

Specialization:
LIFE SCIENCE AND NANOTECHNOLOGY

Qualification

Qualification

Board / University

Year

PhD

Jadavpur University

2010

MSc.

University of Calcutta

2002

BSc.

University of Calcutta

2000

10+2

WBCHSE

1997

10

WBSE

1995

 

Personal Interest

Music, Travelling

Working Experience

Position / Responsibilities

Duration

Organization

 

Associate Dean (FRIC)

01.09.2024-Till date

Assam down town University

Assistant Professor cum Research Faculty

06.02.2024-Till date

Assam down town University

SERB-Research Associate I

17.01.2021-19.11.2023

Indian Association for the Cultivation of Science, Kolkata

Research Associate I

09.12.2019-09.12.2021

Indian Association for the Cultivation of Science, Kolkata

Scientist C

01.02-2019-23.07.2019

Institute of Advanced Study in Science & Technology

SERB-National Post Doctoral Fellow

11.04.2018-24.01.2019

IIT-Guwahati

DBT-Research Associate

01.01.2012-31.12.2016

Bose Institute, Kolkata,

Research Associate

25.08.2010-24.08.2011

National Institute of Immunology, New Delhi

Research

List of Publications (h-Index-12, Citations-1076)

1. Zaman A, GhoshA, GhoshA K, DasP K. 2024. DON encapsulated carbon dot-vesicle conjugate in therapeutic intervention of lung adenocarcinoma by dual targeting of CD44 and SLC1A5. Nanoscale, 16: 21817-21836. (IF: 5.8)

2. Ghosh AK, Ghosh A and Das PK. 2024. Nanotechnology Meets Stem Cell Therapy for Treating Glioblastomas: A Review. ACS Appl. Nano Mater. 7: 2430–2460. (IF: 5.9).

3. Mandal A K, Sarkar S, Ghosh A, Das N. 2024. Inhibitory activity of nanoencapsulated quercetin against sodium arsenite-induced sub-acute liver toxicity in rats. Journal of Drug Delivery and Therapeutics. 14:111-119 (IF: 2.25)

4. Ghosh A, Ghosh AK, Zaman A, Das PK. 2023. Metformin - loaded hyaluronic acid-derived carbon dots for targeted therapy against hepatocellular carcinoma by glutamine metabolic reprogramming. Mol. Pharm. doi:10.1021/acs.molpharmaceut.3c00772, Epub ahead of print. PMID: 37933877. (IF: 5.364)

5. Chowdhury M, Pal S, Ghosh A, Das PK. 2023. Co2+ doped biotinylated carbon dot: A theranostic agent for target specific killing of cancer cells via hypoxia induced apoptosis. Chem. Eur. J. 29: e202300928 (IF: 5.02).

6. Ghosh A, Ghosh AK, Chowdhury M, Das PK. Folic Acid-Functionalized Carbon Dot- Enabled Starvation Therapy in Synergism with Paclitaxel against Breast Cancer. 2022. ACS Appl. Bio Mater. 5: 2389–2402. (IF: 3.25).

7. Kashyap B, Barge SR, Bharadwaj S, Deka B, Rahman S, Ghosh A et al. 2021. Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade. Phytomedicine 93:153761. (IF: 5.34).

8. Barge S, Deka B, Kashyap B, Bharadwaj S, Kandimalla R, Ghosh A et al. 2021. Astragalin mediates the pharmacological effects of Lysimachia candida Lindl on adipogenesis via downregulating PPARG and FKBP51 signalling cascade. Phytotherapy Research. 2021: 1–14. (IF: 5.882).

9. Ghosh A* and Banerjee T. 2020. Nanotized curcumin‐benzothiophene conjugate: A potential combination for treatment of cerebral malaria. IUBMB Life. 2020:1-14. (IF: 3.885). (*Corresponding Author).

10. Bhowmik A, Chakravarti S, Ghosh A, Shaw R, Bhandari S, Bhattacharya S, Sen PC, Ghosh MK. 2017. Anti-SSTR2 Peptide based targeted delivery of potent PLGA encapsulated 3,3´- diindolylmethane nanoparticles through blood brain barrier prevents glioma progression. Oncotarget. 8:65339-65358. (IF: 5.168).

11. Bhandary S, Bhowmik A, Ghosh A, Saha S, Pal U, Roy N, Chakraborty N, Chakraborty A, Ghosh M K and Sen P C. 2017. Targeting IL-6/IL-6R Signaling Axis in Triple-Negative Breast Cancer by a Novel Nifetepimine-Loaded Cascade pH Responsive Mesoporous Silica Based Nanoplatform. Global journal of Nanomedicine. 3:1-24.

12. Ghosh A, Bhowmik A, Bhandary S, Putatunda S, Laskar A, Biswas A, Dolui S, Banerjee B, Khan R, Das N, Chakraborty A, Ghosh MK, Sen PC. 2016. Formulation and antitumorigenic activities of nanoencapsulated nifetepimine: A promising approach in treating triple negative breast carcinoma. Nanomedicine: Nanotechnology, Biology and Medicine. 12:1973–1985. (IF: 6.458).

13. Ghosh A, Banerjee T, Bhandary S, Surolia A. 2014. Formulation of nanotized curcumin and demonstration of its antimalarial efficacy. International Journal of Nanomedicine. 9:5373-5387. (IF: 6.4).

14. Mandal A.K., Ghosh D, Sarkar S, Ghosh A, Swarnakar S, Das N. 2014. Nanocapsulated quercetin downregulates rat hepatic MMP-13 and controls diethylnitrosamine-induced carcinoma. Nanomedicine. 9(15):2323-37. (IF: 5.307)

15. Ghosh A, Sarkar S, Mandal A.K. and Das N. 2013. Neuroprotective role of nanoencapsulated quercetin in combating ischemia-reperfusion induced neuronal damage in young and aged rats. PLOS ONE. (DOI: 10.1371/journal.pone.0057735). (IF: 3.04).

16. Ghosh A, Ghosh D, , Sarkar S, Mandal AK, Thakur Choudhury S and Das N. 2012. Anticarcinogenic     activity     of       nanoencapsulated quercetin in combating diethylnitrosamine induced hepatocarcinoma in rats. European Journal of Cancer Prevention. 21(1): 32-41. (IF: 2.497).

17. Ghosh D, Thakur Choudhury S, Ghosh S, Mandal A K, Sarkar S, Ghosh A, Das Saha K, Das N. 2012. Nanocapsulated Curcumin: Oral Chemopreventive Formulation against Diethylnitrosamine induced Hepatocellular Carcinoma in rat. Chemico Biological Interactions. 195: 206-214. (IF: 5.192).

18. Ghosh A and Surolia A. 2011. Gamma-secretase activating protein is a therapeutic target for alzheimer’s disease: A path-breaking discovery finally paving way towards therapeutic intervention. Annals of Neuroscience. 18(1) (SJR:0.588).

19. Ghosh A, Mandal AK, Sarkar S and Das N. 2011. Hepatoprotective and neuroprotective activity of liposomal quercetin in combating chronic arsenic induced oxidative damage in liver and brain of rats. Drug Delivery. 18(6): 451-459. (IF: 6.419).

20. Ghosh D, Ghosh S, Sarkar S, Ghosh A, Mandal AK, Das Saha K and Das N. 2010. Quercetin in vesicular delivery systems: Evaluation in combating arsenic-induced acute liver toxicity associated gene expression in rat model. Chemico–Biological Interactions. 186, 61-71. (IF: 5.192)

21. Ghosh A, Mandal AK, Sarkar S, Panda S and Das N. 2009. Nanoencapsulation of Quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of rats. Life Sciences. 84, 75-80. (IF: 5.037)

22. Das S, Mandal AK, Ghosh A, Panda S, Das N and Sarkar S. 2008. Nanoparticulated Quercetin in combating age related cerebral oxidative injury. Current Aging Science. 1, 169-174. (IF: 1.78)

 

Awards & Achievements

  • Awarded SERB-National Post Doctoral Fellowship supported by Science & Engineering Research Board, Department of Science & Technology, Govt. of India (April, 2018).
  • Awarded DBT-Research Associate supported by Department of Biotechnology, Govt. of India (January, 2012).
  • Awarded ICMR-Senior Research Fellowship supported by Indian Council of Medical Research, Govt. of India (May, 2006).
  • Awarded Second Prize for Best Poster Award at the Workshop on Biomaterials and Biomedical Devices on Dec 12-13, 2006 held at CGCRI, Kolkata, India.